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Year 1 Research Project
Digital Twin and Machine-Learning for Optimized Pathogen Contact-Tracing Sanitation and Decontamination

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Description

BACKGROUND

Food safety can ultimately depend on how pathogens are transmitted through the air or are passed along through consecutive surface touches. Surface transmission is further complicated by thin biofilms on food processing surfaces. By developing digital twin and machine learning algorithms, effective mitigation and treatments can be more accurately applied.

GOALS

  • Create and validate a digital twin model simulating the spread of viral pathogens through droplets under simulated food facility conditions.
  • Create and validate a digital twin model simulating the spread of Listeria in a food processing facility based on interactions among people, equipment, and food products.

  • Apply machine learning models in the detection of biofilms on food contact surfaces using imaging/spectroscopic approaches.
  • Create and apply digital twin models of light propagation and biofilm absorbance to deliver adequate dosimetry for the inactivation of viral particles.

IMPACT

  • Worker safety can be better protected at food processing facilities through modeling and management of aerosols.
  • Consumer safety can be increased through more targeted decontamination of biofilms.

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Photos

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Team

Portrait of Tarek Zohdi

Tarek Zohdi

Principal Investigator

Portrait of Nitin Nitin

Nitin Nitin

Co Principal Investigator

Portrait of Rebecca Abergel

Rebecca Abergel

Collaborator

Portrait of Ana Arias

Ana Arias

Collaborator

Portrait of Renata Ivanek

Renata Ivanek

Collaborator

Portrait of Xin Liu

Xin Liu

Collaborator

Portrait of Simo Mäkiharju

Simo Mäkiharju

Collaborator

Portrait of Christopher Simmons

Christopher Simmons

Collaborator

Portrait of Ilias Tagkopoulos

Ilias Tagkopoulos

Collaborator

Portrait of Luxin Wang

Luxin Wang

Collaborator

Portrait of Martin Wiedmann

Martin Wiedmann

Collaborator

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Publications

A thumbnail of the journal or conference cover of Modeling bioaffinity-based targeted delivery of antimicrobials to Escherichia coli biofilms using yeast microparticles. Part I: Model development and numerical simulation
Journal Article ⏐ Biotechnol. Bioeng. 2022

Modeling Bioaffinity-based Targeted Delivery of Antimicrobials to Escherichia Coli Biofilms Using Yeast Microparticles. Part I: Model Development and Numerical Simulation

Yi, Jiyoon,Kang Huang,and Nitin Nitin
A thumbnail of the journal or conference cover of Effect of coherent structures on particle transport and deposition from a cough
Journal Article ⏐ Aerosol Sci. Technol. 2022

Effect of Coherent Structures on Particle Transport and Deposition From a Cough

Thacher, Eric,and Simo A Mäkiharju
DOI: 10.1080/02786826.2022.2044449
A thumbnail of the journal or conference cover of Machine learning analysis of phage oxidation for rapid verification of wash water sanitation
Journal Article ⏐ Postharvest Biol. Technol. 2021

Machine Learning Analysis of Phage Oxidation for Rapid Verification of Wash Water Sanitation

Cui, Hemiao,Reza Ovissipour,Xu Yang,and Nitin Nitin
DOI: 10.1016/j.postharvbio.2021.111654
A thumbnail of the journal or conference cover of Modeling bioaffinity‐based targeted delivery of antimicrobials to Escherichia coli biofilms using yeast microparticles. Part II: Parameter evaluation and validation
Journal Article ⏐ Biotechnol. Bioeng. 2022

Modeling Bioaffinity‐based Targeted Delivery of Antimicrobials to Escherichia Coli Biofilms Using Yeast Microparticles. Part II: Parameter Evaluation and Validation

Yi, Jiyoon,Kang Huang,and Nitin Nitin
DOI: 10.1002/bit.27969
A thumbnail of the journal or conference cover of Spectroscopy Approaches for Food Safety Applications: Improving Data Efficiency Using Active Learning and Semi-supervised Learning
Journal Article ⏐ Front. Artif. Intell. 2022

Spectroscopy Approaches for Food Safety Applications: Improving Data Efficiency Using Active Learning and Semi-supervised Learning

Zhang, Huanle,Nicharee Wisuthiphaet,Hemiao Cui,Nitin Nitin,Xin Liu,and Qing Zhao
DOI: 10.3389/frai.2022.863261