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Year 1 Research Project
Predicting Health Effects from Food Composition via Large-Scale Information Extraction

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Description

BACKGROUND

Much work has been done to systematically store food composition information beyond the ~160 nutrients quantified in USDA food composition tables. FoodDB has approximately 800 foods and approximately 70,000 known and predicted compounds, of which approximately 15,000 have been observed in food. The literature curation required to populate FoodDB and other similar databases is a manual and error-prone effort. As a result, FoodDB and similar databases still suffer from the existence of “nutritional dark matter”, compounds that are reported in papers but are not quantified in any centralized database. While private and academic efforts have been made to predict health effects from food, there is no approach so far that integrates large-scale automated text mining with machine learning to augment predictive capability.

GOALS

  • Create a software package for the automated curation of nutrition data from published papers
  • Apply the software package to a corpus of hundreds of food and nutrition papers, and organize the resulting information in a Knowledge Base (KB)
  • Use the novel KB to augment published datasets linking food intake to health outcomes to create a predictor of health effects from chemical composition of food.

IMPACT

  • Create a healthier food system by understanding what food is and what it does to our health state
  • Reveal the food composition information hidden in published papers and integrating it to a KB
  • Provide a way to organize, interrogate and connect this data trove to other data resources that together can be used to link food and health states

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Team

Portrait of Ilias Tagkopoulos

Ilias Tagkopoulos

Principal Investigator

Portrait of Gabriel Simmons

Gabriel Simmons

Co Principal Investigator

Portrait of Fangzhou Li

Fangzhou Li

Co Principal Investigator

Portrait of Jason Youn

Jason Youn

Co Principal Investigator

Portrait of Danielle Lemay

Danielle Lemay

Co Principal Investigator

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Publications

A thumbnail of the journal or conference cover of Methane and fatty acid metabolism pathways are predictive of Low-FODMAP diet efficacy for patients with irritable bowel syndrome
Journal Article ⏐ Clin. Nutr. 2021

Methane and Fatty Acid Metabolism Pathways Are Predictive of Low-FODMAP Diet Efficacy for Patients with Irritable Bowel Syndrome

Eetemadi, Ameen,and Ilias Tagkopoulos
DOI: 10.1016/j.clnu.2020.12.041
A thumbnail of the journal or conference cover of Preliminary Techno-Economic Assessment of Animal Cell-Based Meat
Journal Article ⏐ Foods 2020

Preliminary Techno-Economic Assessment of Animal Cell-Based Meat

Risner, Derrick,Fangzhou Li,Jason S Fell,Sara A Pace,Justin Siegel,Ilias Tagkopoulos,and Edward S Spang
DOI: 10.3390/foods10010003
A thumbnail of the journal or conference cover of Using Word Embeddings to Learn a Better Food Ontology
Journal Article ⏐ Front. Artif. Intell. 2020

Using Word Embeddings to Learn a Better Food Ontology

Youn, Jason,Tarini Naravane,and Ilias Tagkopoulos
DOI: 10.3389/frai.2020.584784